Freddie Martin

bioRxiv · de novo binders · CAR-T · benchmarking

A global competition benchmarking de novo binder design as CAR-T binding domains against human CD20. 12,000 designs from 42 countries were screened by pooled CAR-T proliferation, with retrospective filters nearly doubling success rates.

bioRxiv · cryo-EM · bioinformatics

High-resolution cryo-EM structure of an extracellular contractile injection system, revealing a unique sheath architecture and a previously unannotated cluster of CISs. Contributed bioinformatic analysis and wet-lab support.

protein design · machine learning · team leadership

Designed binders against a cancer antigen target as part of the AmigoAcids team in the UT Austin BioML Society challenge. Combined a wide variety of AI design tools with a uniform validation pipeline, achieving a 6 % (11/187) hit rate in the proliferation screen and placing 2nd overall. Helped lead a remote, international team and mentored newer members on protein design fundamentals.

Blender · ChimeraX · scientific communication

Renders and graphical abstracts that aim to capture the function and beauty of biological macromolecules — from membrane transporters to contractile injection systems. Get in touch if you'd like to commission or collaborate on a piece.

The Social Mobility Foundation

Mentoring aspiring students from diverse socioeconomic backgrounds who are pursuing higher education and careers in biology and chemistry — providing personalised advice on university applications, career pathways and professional skills.

Pint of Science Denmark

Coordinated logistics and hosted Pint of Science Copenhagen at the Dispensary.